Patient Stories

HEAR FROM PEOPLE
WHO ARE TAKING BRIUMVI

Discover how BRIUMVI is impacting real people with RMS. Hear from people who have included it in their RMS treatment journey.

HEAR FROM PEOPLE WHO ARE TAKING BRIUMVI

Discover how BRIUMVI is impacting real people with RMS. Hear from people who have included it in their RMS treatment journey.

HEAR FROM PEOPLE WHO ARE TAKING BRIUMVI

 

Discover how BRIUMVI is impacting real people with RMS. Hear from people who have included it in their RMS treatment journey.

These individual stories feature people who have taken BRIUMVI for their RMS – either as a first treatment or after trying other options. Hear why thousands of people, like Mandy, Alex and Meaghan, chose BRIUMVI to take on their RMS.

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“When I found out that BRIUMVI was a 1-hour infusion twice a year after the starting dose, I was really drawn to choosing that as my DMT. I have two girls and it’s nice that I can get my infusions while they’re at school and it doesn’t interrupt my time with them.”

 

Mandy, Living with RMS and taking BRIUMVI

Individual results may vary

“Being on an effective medication for my RMS was important to me because I have two young daughters to raise. I feel like BRIUMVI is the right choice for me.”

 

Alex, Living with RMS and taking BRIUMVI

Individual results may vary

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“Being on an effective medication for my RMS was important to me because I have two young daughters to raise. I feel like BRIUMVI is the right choice for me.”

 

Alex, Living with RMS and taking BRIUMVI

Individual results may vary

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“I love doing anything I can possibly do outside. Aside from the 1-hour infusion time after the first dose, I did my own research, and I was impressed by the efficacy and the safety of BRIUMVI. That is what ultimately led my doctor and I to choose BRIUMVI.”

 

Meaghan, Living with RMS and taking BRIUMVI

Individual results may vary

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Pierre

Categories: BRIUMVI as 1st treatment

During a midday stroll in June 2023, I noticed that my right foot wasn’t lifting normally. A few weeks later, people were commenting that I was limping. Soon afterwards, the right portion of my torso went numb, and I started experiencing bladder problems. At this point, I went to urgent care. After several tests where my heart and lungs were deemed fine, they prescribed me steroids in case my difficulty breathing was due to inflammation. My wife was still concerned, so finally I visited my primary care physician. After explaining my last two months to him, he ordered blood tests and an MRI and made a referral to an MS specialist. After more blood tests, a couple more MRIs and a host of neurological tests, I was diagnosed with RMS in mid-September of 2023.

During the weeks between my visit with my primary care physician and neurologist, I read every publication I could find about MS. The more I learned, the more it became a reality to me that an MS diagnosis was probably around the corner and so I shifted my research to treatment options.

When my neurologist presented treatment options to me, I asked him about BRIUMVI. The results of the clinical trials were encouraging, and that coupled with a 1-hour infusion every 24 weeks after a loading dose made it appealing to me as a treatment option. A couple of days after my diagnosis, I set off for a two-week trip to visit friends and family in Europe. Before I left, my neurologist put me on a treatment to get me through the trip and to my first infusion. While I was out of the country, the BRIUMVI Patient Support team and my neurologist’s office worked together to have everything lined up for me a couple of days after my return.

I have discovered an amazing community of MS warriors. I have reached out for support to a local nonprofit and reconnected with old friends near and far who I discovered have been living with MS. I have learned a lot while on my MS journey so far, and I know I will learn so much more as time goes on.

 

 

Pierre

My life journey has taken me across the globe; from Hong Kong to Tokyo, England, Honduras, Vanuatu, Madagascar, and Montreal. I finally landed in the USA a little over 15 years ago. I’m married to an incredible person, work full time, have two dogs, and I’m an MS Warrior.

Matt

Categories: BRIUMVI as 1st treatment

My journey with MS began with a series of misdiagnoses. It all started in 2020 on a mission trip when I experienced numbness, tingling on my left side, and severe vertigo. I ended up in the emergency room, where doctors diagnosed me with dehydration and a concussion. In 2021, just as I was about to start college, the numbness returned, along with hearing loss in my left ear. Two years later, while studying for finals, I woke up with a pounding headache and a swollen tongue. Frustrated by the lack of answers, I sought a second opinion. This doctor recognized signs of a seizure and ordered tests that revealed brain lesions consistent with Relapsing Multiple Sclerosis.

After hearing this diagnosis, I spent about a week focused on my future and mourning my potential. I was feeling down and felt like I was living on borrowed time. During my next MRI scans, I asked the technician about DMTs. He mentioned a few options and recommended visiting the nearby MS specialty clinic for more information. After my scans, I walked in and secured an appointment. In the meantime, I also spoke with one of my college professors who, upon hearing of my recent MS diagnosis, reassured me that treatment options have come such a long way.

The MS specialist reviewed my MRIs and discussed DMTs. I told her I was determined to fight it aggressively and refused to give up on my dreams. That’s when she introduced BRIUMVI. I did my homework and learned more about BRIUMVI on my own, and my doctor and I decided together that I would start BRIUMVI in May of 2023. What appealed to me about BRIUMVI was that it requires 1-hour infusions approximately every 6 months after the initial loading dose. Also, the BRIUMVI Patient Support program helped me navigate insurance coverage and provided me with options for financial assistance.

Before my MS diagnosis, I didn’t know much about or know many people living with it. But now, when I talk to others, more and more people tell me they have a friend or family member with MS. I am confident and excited about my future, and I won’t let MS hold me back. My goals are to continue pursuing my dream of becoming a doctor, playing sports, weightlifting, hiking, and traveling.

 

 

Matt

I am a medical school student in my mid-twenties. Before my RMS diagnosis, I was active in sports, weightlifting, hiking, and traveling, and those things are still important to me today.

Jesyka

Categories: BRIUMVI as 1st treatment

At the onset of my symptoms, I started to have vision problems. A few days later, my legs started to feel a bit weak, and I felt lightheaded. Eventually, I was experiencing numbness throughout my body. That’s when I knew I needed to figure out what was going on. I went to the ER and the neurologist told me it was MS, something I knew nothing about at the time. I have always been able to fix everything for everyone around me, and at this moment, I did not know how to fix myself.

During the first few months after my diagnosis, I spent countless hours researching and learning all I could about MS and the different treatments. I studied clinical trials and read up on various treatment options, including BRIUMVI.

I was relieved when my neurologist mentioned BRIUMVI, as I was interested in this treatment. We decided that BRIUMVI would be the best option for me and we scheduled my first treatment. I was nervous about how my body was going to handle my first infusion, but optimistic about what BRIUMVI could offer. I was pleased with how my body handled this infusion, and I left the infusion center feeling like I was on the right treatment path for me. I’ve had multiple infusions since that first one, and my doctor feels like BRIUMVI is working for me.

I have learned, adapted and changed many aspects of my life, and I try to listen to my body every minute of every day. I have had moments where I have felt a sense of jealousy towards the “old me”, the me that could do whatever it was she wanted without a care in the world. I am a firm believer that everything happens for a reason, and positivity is always #1 in my life. The hard and sad times are steppingstones that I turn into positive lessons on how to be better and keep growing. I am grateful to share my story and be a part of the change.

 

 

Jesyka

I am an Engineering and Analysis Supervisor. I love to work, and I love my job. When I am not working, I enjoy spending time with my family. My support system consists of my wife, my mom, my sisters, cousins, and closest friends. Helping people and being counted on is what gives me life!

SHARE YOUR BRIUMVI STORY

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BRIUMVI Patient Support

Discover a flexible program designed to support the treatment journey in a way that works best for you.

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FINANCIAL ASSISTANCE

No matter what type of health insurance you have, there may be support to help you afford BRIUMVI. Options may be available for you even if you have no health insurance at all. Learn about the potential options.

People featured on this page are taking BRIUMVI and have been compensated by TG Therapeutics for their time.

INDICATION AND IMPORTANT
SAFETY INFORMATION

Who should not receive BRIUMVI?

Do not receive BRIUMVI if you have an active hepatitis B virus (HBV) infection.

Do not receive BRIUMVI if you have had a life-threatening allergic reaction to BRIUMVI. Tell your healthcare provider if you have had an allergic reaction to BRIUMVI or any of its ingredients in the past.

What is the most important information I should know
about BRIUMVI?

BRIUMVI can cause serious side effects, including:

Infusion reactions: Infusion reactions are one of the most common side effects of BRIUMVI, which can be serious and may require you to be hospitalized. You will be monitored during your infusion and may be monitored after each infusion of BRIUMVI for signs and symptoms of an infusion reaction. Tell your healthcare provider if you get any of these symptoms:

  • fever
  • chills
  • headache
  • flu-like symptoms
  • fast heartbeat
  • hives
  • itchy skin
  • dizziness
  • feeling faint
  • swelling of tongue or throat
  • trouble breathing
  • wheezing
  • nausea
  • abdominal pain
  • throat irritation
  • redness of the face or skin

These infusion reactions can happen over 24 hours after your infusion. It is important that you call your healthcare provider right away if you get any of the signs or symptoms listed above after each infusion. If you get an infusion reaction, your healthcare provider may need to stop or slow down the rate of your infusion.

  • Infection:
    • Infections are a common side effect, and upper respiratory tract infections are one of the most common side effects of BRIUMVI. BRIUMVI increases your risk of getting infections caused by bacteria or viruses that may be life-threatening or cause death. Tell your healthcare provider if you have an infection or have any of the following signs of infection including fever, chills, a cough that does not go away, or painful urination. Your healthcare provider should delay your treatment with BRIUMVI until your infection is gone.
    • Hepatitis B virus (HBV) reactivation: Before starting treatment with BRIUMVI, your healthcare provider will do blood tests to check for hepatitis B viral infection. If you have ever had hepatitis B virus infection, the hepatitis B virus may become active again during or after treatment with BRIUMVI. Hepatitis B virus becoming active again (called reactivation) may cause serious liver problems including liver failure or death. Your healthcare provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after you stop receiving BRIUMVI.
    • Weakened immune system: BRIUMVI taken before or after other medicines that weaken the immune system could increase your risk of getting infections.
    • Progressive Multifocal Leukoencephalopathy (PML): PML may happen with BRIUMVI. PML is a rare, serious brain infection caused by a virus that may get worse over days or weeks. PML can result in death or severe disability. Tell your healthcare provider right away if you have any new or worsening neurologic signs or symptoms. These symptoms may include weakness on one side of your body, loss of coordination in arms and legs, vision problems, changes in thinking and memory which may lead to confusion, and personality changes.
  • Low immunoglobulins: BRIUMVI may cause a decrease in some types of antibodies. Your healthcare provider will do blood tests to check your blood immunoglobulin levels.

Before receiving BRIUMVI, tell your healthcare provider about all of your medical conditions, including if you:

  • have or think you have an infection.
  • take or plan to take medicines that affect your immune system. These medicines may increase your risk of getting an infection.
  • have ever had hepatitis B or are a carrier of the hepatitis B virus.
  • have had a recent vaccination or are scheduled to receive any vaccinations.
    • You should receive any required ‘live’ or ‘live-attenuated’ vaccines at least 4 weeks before you start treatment with BRIUMVI. You should not receive ‘live’ or ‘live-attenuated’ vaccines while you are being treated with BRIUMVI and until your healthcare provider tells you that your immune system is no longer weakened.
    • When possible, you should receive any ‘non-live’ vaccines at least 2 weeks before you start treatment with BRIUMVI. If you would like to receive any non-live vaccines while you are being treated with BRIUMVI, talk to your healthcare provider.
    • If you have a baby and you received BRIUMVI during your pregnancy, it is important to tell your baby’s healthcare provider about receiving BRIUMVI so they can decide when your baby should be vaccinated.
  • are pregnant, think that you might be pregnant, or plan to become pregnant. BRIUMVI may harm your unborn baby. You should use birth control (contraception) during treatment with BRIUMVI and for at least 6 months after your last infusion of BRIUMVI. Talk with your healthcare provider about what birth control method is right for you during this time.
  • are breastfeeding or plan to breastfeed. It is not known if BRIUMVI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take BRIUMVI.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of BRIUMVI?

The most common side effects of BRIUMVI include:

Infusion reactions, upper and lower respiratory tract infections, herpes infections, extremity pain, insomnia, and fatigue.

These are not all the possible side effects of BRIUMVI. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to TG Therapeutics at 1-877-TGTXINC (1-877-848-9462).

For more important information, go to www.briumvi.com or call 1-833-BRIUMVI (1-833-274-8684).

Indication

BRIUMVI is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

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Important Safety Information
Who should not receive BRIUMVI?
  • Do not receive BRIUMVI if you have an active hepatitis B virus (HBV) infection.
  • Do not receive BRIUMVI if you have had a life-threatening allergic reaction to BRIUMVI.
Indication
BRIUMVI is indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

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