Patient Stories

HEAR FROM PEOPLE
WHO ARE TAKING BRIUMVI

HEAR FROM PEOPLE WHO ARE TAKING BRIUMVI

HEAR FROM PEOPLE WHO ARE TAKING BRIUMVI

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People featured on this page are taking BRIUMVI and have been compensated by TG Therapeutics for their time.

People featured on this page are taking BRIUMVI and have been compensated by TG Therapeutics for their time.

These individual stories feature people who have taken BRIUMVI for their RMS – either as a first treatment or after trying other options. Hear why thousands of people, like Mandy, Alex and Meaghan, chose BRIUMVI to take on their RMS.

These individual stories feature people who have taken BRIUMVI for their RMS – either as a first treatment or after trying other options. Hear why thousands of people, like Mandy, Alex and Meaghan, chose BRIUMVI to take on their RMS.

Mandy, on the BRIUMVI dosing schedule

Danté, on BRIUMVI financial assistance

Taylor, on her journey from diagnosis to BRIUMVI

Alex, on why BRIUMVI was the right choice for him

Meaghan, on researching treatment options

Jules, on switching from once-a-day oral to BRIUMVI

See All Stories

Julie, a person with RMS taking BRIUMVI® (ublituximab-xiiy)

Julie

Categories: Switched to BRIUMVI

In the year 2000, I ran the Pittsburgh marathon. In the year 2004, I could barely walk across the room. After going through tests, questioning what was wrong, and the fear that I was having a dream that was quickly turning into a nightmare, I was given my RMS diagnosis.

Despite being proactive and approaching this head-on, I faced challenges with certain treatments along the way. Initially I tried injections, but unfortunately, I did not experience the desired results. I then made the choice to begin an infusion and then eventually an oral medication. These treatments did not halt the disease, as an MRI confirmed I had a new lesion.

My neurologist and I decided we needed to look into other therapies because the landscape of RMS had changed dramatically since 2004. In April 2023, I started BRIUMVI. I have been on a variety of treatments, and I’m happy that I have found BRIUMVI, a 1-hour, twice-a-year infusion after the starting dose. For me, my infusions went smoothly, and my doctor thinks I am doing well.

With RMS, I can still do my job on a part-time basis, and that is good enough for me right now! It’s still ‘game on’, and BRIUMVI is doing what I had hoped it would do for me.

Julie

I am an athletic trainer, and my days consist of doing yoga, stretching, and working on flexibility with all the sports teams at a local college. I enjoy spending time with my husband, cooking, volunteering, and taking my dog for walks.

Whitney, a person with RMS taking BRIUMVI® (ublituximab-xiiy)

Whitney

Categories: Switched to BRIUMVI

I started having eye issues including pain and severe light sensitivity. Then, one day, the left side of my body went numb. While I thought that was weird, nothing hurt, so I just kept going. I eventually got an appointment with a doctor, as it seemed to be getting worse. By that point, I couldn’t walk or stand up for long periods of time. My husband had to help me walking into the appointment. Thinking I might have a disease, the doctor sent me immediately for an MRI of my brain, cervical spine and T-spine, with and without contrast. He called me the next day and told me I had Relapsing Multiple Sclerosis. I had no idea what RMS was, and I was devastated.

It took me awhile to find the right MS specialist, but once I did, we began discussing treatment options. My first treatment was an injectable medication. I was hopeful. I really wanted that injectable medication to work. However, MRIs showed multiple active lesions after several months on that medication, so my MS specialist suggested switching medications.

After going over various treatment options, my neurologist suggested BRIUMVI. I was hesitant to switch at first, but my neurologist was very hopeful. She had several patients on it who had seen results. Based on my last MRI, my doctor feels like BRIUMVI is working for me. I didn’t have any active lesions or any new lesions.

My RMS diagnosis was tough, but I pulled out of that negative headspace by staying active. I want to show people that I have RMS, but RMS doesn’t have me. Getting on the right medication can make the difference! I’m thankful that my doctor suggested switching medications and I’m grateful to have a treatment that works for me!

 

 

Whitney

I’ve been a teacher for over 20 years, and I’m a mother of 6 adult children. I’m a certified personal trainer as well as a nutrition coach, and recently I have taken an interest in cycling. I’ve cycled close to 2,000 miles on my bike and hope to continue to ride more over the years. Staying active is very important to me.

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Financial Assistance

No matter what type of health insurance you have, there may be support to help you afford BRIUMVI. Options may be available for you even if you have no health insurance at all. Learn about the potential options.

INDICATION AND IMPORTANT
SAFETY INFORMATION

Who should not receive BRIUMVI?

Do not receive BRIUMVI if you have an active hepatitis B virus (HBV) infection.

Do not receive BRIUMVI if you have had a life-threatening allergic reaction to BRIUMVI. Tell your healthcare provider if you have had an allergic reaction to BRIUMVI or any of its ingredients in the past.

What is the most important information I should know
about BRIUMVI?

BRIUMVI can cause serious side effects, including:

  • Infusion reactions: Infusion reactions are one of the most common side effects of BRIUMVI, which can be serious and may require you to be hospitalized. You will be monitored during your infusion and may be monitored after each infusion of BRIUMVI for signs and symptoms of an infusion reaction. Tell your healthcare provider if you get any of these symptoms:
    • fever
    • chills
    • headache
    • flu-like symptoms
    • fast heartbeat
    • hives
    • itchy skin
    • dizziness
    • feeling faint
    • swelling of tongue or throat
    • trouble breathing
    • wheezing
    • nausea
    • abdominal pain
    • throat irritation
    • redness of the face or skin

These infusion reactions can happen over 24 hours after your infusion. It is important that you call your healthcare provider right away if you get any of the signs or symptoms listed above after each infusion. If you get an infusion reaction, your healthcare provider may need to stop or slow down the rate of your infusion.

  • Infection:
    • Infections are a common side effect, and upper respiratory tract infections are one of the most common side effects of BRIUMVI. BRIUMVI increases your risk of getting infections caused by bacteria or viruses that may be life-threatening or cause death. Tell your healthcare provider if you have an infection or have any of the following signs of infection including fever, chills, a cough that does not go away, or painful urination. Your healthcare provider should delay your treatment with BRIUMVI until your infection is gone.
    • Hepatitis B virus (HBV) reactivation: Before starting treatment with BRIUMVI, your healthcare provider will do blood tests to check for hepatitis B viral infection. If you have ever had hepatitis B virus infection, the hepatitis B virus may become active again during or after treatment with BRIUMVI. Hepatitis B virus becoming active again (called reactivation) may cause serious liver problems including liver failure or death. Your healthcare provider will monitor you if you are at risk for hepatitis B virus reactivation during treatment and after you stop receiving BRIUMVI.
    • Weakened immune system: BRIUMVI taken before or after other medicines that weaken the immune system could increase your risk of getting infections.
    • Progressive Multifocal Leukoencephalopathy (PML): PML is a rare, serious brain infection caused by a virus that may get worse over days or weeks. PML can result in death or severe disability. PML has been reported with BRIUMVI. Tell your healthcare provider right away if you have any new or worsening neurologic signs or symptoms. These symptoms may include weakness on one side of your body, loss of coordination in arms and legs, vision problems, changes in thinking and memory which may lead to confusion, and personality changes.
  • Low immunoglobulins: BRIUMVI may cause a decrease in some types of antibodies. Your healthcare provider will do blood tests to check your blood immunoglobulin levels.

Before receiving BRIUMVI, tell your healthcare provider about all of your medical conditions, including if you:

  • have or think you have an infection.
  • take or plan to take medicines that affect your immune system. These medicines may increase your risk of getting an infection.
  • have ever had hepatitis B or are a carrier of the hepatitis B virus.
  • have a history of liver problems.
  • have had a recent vaccination or are scheduled to receive any vaccinations.
    • You should receive any required ‘live’ or ‘live-attenuated’ vaccines at least 4 weeks before you start treatment with BRIUMVI. You should not receive ‘live’ or ‘live-attenuated’ vaccines while you are being treated with BRIUMVI and until your healthcare provider tells you that your immune system is no longer weakened.
    • When possible, you should receive any ‘non-live’ vaccines at least 2 weeks before you start treatment with BRIUMVI. If you would like to receive any non-live vaccines while you are being treated with BRIUMVI, talk to your healthcare provider.
    • If you have a baby and you received BRIUMVI during your pregnancy, it is important to tell your baby’s healthcare provider about receiving BRIUMVI so they can decide when your baby should be vaccinated.
  • are pregnant, think that you might be pregnant, or plan to become pregnant. It is not known if BRIUMVI will harm your unborn baby. You should use birth control (contraception) during treatment with BRIUMVI and for at least 6 months after your last infusion of BRIUMVI. Talk with your healthcare provider about what birth control method is right for you during this time.
  • are breastfeeding or plan to breastfeed. It is not known if BRIUMVI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take BRIUMVI.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of BRIUMVI?

BRIUMVI may cause serious side effects, including:

• See “What is the most important information I should know about BRIUMVI?”

Liver damage. BRIUMVI may cause liver damage. Your healthcare provider will do blood tests to check your liver before you start BRIUMVI and while you take BRIUMVI if needed. Tell your healthcare provider right away if you have any symptoms of liver damage, such as:

    • yellowing of the skin and eyes (jaundice)
    • nausea
    • vomiting
    • unusual darkening of the urine
    • feeling tired or weak

The most common side effects of BRIUMVI include:

  • Infusion reactions, upper and lower respiratory tract infections, herpes infections, extremity pain, insomnia, and fatigue.

These are not all the possible side effects of BRIUMVI. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to TG Therapeutics at 1-877-TGTXINC (1-877-848-9462).

For more important information, go to www.briumvi.com or call 1-833-BRIUMVI (1-833-274-8684).

Indication

BRIUMVI is a prescription medication used to treat adults with relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapse-remitting disease, and active secondary progressive disease.

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Important Safety Information
Who should not receive BRIUMVI?
  • Do not receive BRIUMVI if you have an active hepatitis B virus (HBV) infection.
  • Do not receive BRIUMVI if you have had a life-threatening allergic reaction to BRIUMVI. Tell your healthcare provider if you have had an allergic reaction to BRIUMVI or any of its ingredients in the past.
Indication
BRIUMVI is a prescription medication used to treat adults with relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapse-remitting disease, and active secondary progressive disease.

Click or scroll to see IMPORTANT SAFETY INFORMATION AND INDICATION

Important Safety Information
Who should not receive BRIUMVI?
  • Do not receive BRIUMVI if you have an active hepatitis B virus (HBV) infection.
  • Do not receive BRIUMVI if you have had a life-threatening allergic reaction to BRIUMVI. Tell your healthcare provider if you have had an allergic reaction to BRIUMVI or any of its ingredients in the past.